DAMGO
SMILES | None |
InChIKey | HPZJMUBDEAMBFI-WTNAPCKOSA-N |
Sequence | YAGFG |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Human | Opioid | A | pKi | 6.5 | 6.5 | 6.5 | Guide to Pharmacology |
μ | OPRM | Human | Opioid | A | pKi | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
μ | OPRM | Rat | Opioid | A | pKi | 8.7 | 8.7 | 8.7 | Guide to Pharmacology |
κ | OPRK | Rat | Opioid | A | pKi | 5.9 | 5.9 | 5.9 | Guide to Pharmacology |
μ | OPRM | Mouse | Opioid | A | pKi | 8.64 | 9.02 | 9.34 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pKi | 7.8 | 8.76 | 9.28 | ChEMBL |
μ | OPRM | Human | Opioid | A | pKi | 5.66 | 8.75 | 9.55 | ChEMBL |
CCK2 | GASR | Human | Cholecystokinin | A | pKi | 7.96 | 7.96 | 7.96 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 5.82 | 6.47 | 9.18 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKd | 5.73 | 5.73 | 5.73 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 6.51 | 6.53 | 6.57 | ChEMBL |
κ | OPRK | Guinea pig | Opioid | A | pKi | 5.24 | 5.49 | 5.74 | ChEMBL |
κ | OPRK | Guinea pig | Opioid | A | pKd | 6.29 | 6.29 | 6.29 | ChEMBL |
NOP | OPRX | Guinea pig | Opioid | A | pKi | 7.57 | 7.57 | 7.57 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
μ | OPRM | Mouse | Opioid | A | pIC50 | 7.12 | 8.09 | 8.86 | ChEMBL |
μ | OPRM | Mouse | Opioid | A | pEC50 | 7.72 | 8.01 | 8.3 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pIC50 | 7.44 | 8.3 | 9.0 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pEC50 | 6.31 | 7.41 | 9.59 | ChEMBL |
μ | OPRM | Human | Opioid | A | pIC50 | 7.7 | 8.7 | 9.37 | ChEMBL |
μ | OPRM | Human | Opioid | A | pEC50 | 6.42 | 7.67 | 9.52 | ChEMBL |
CCK2 | GASR | Human | Cholecystokinin | A | pEC50 | 8.57 | 8.57 | 8.57 | ChEMBL |
δ | OPRD | Human | Opioid | A | pIC50 | 8.84 | 8.84 | 8.84 | ChEMBL |
δ | OPRD | Human | Opioid | A | pEC50 | 6.4 | 7.28 | 8.16 | ChEMBL |
κ | OPRK | Human | Opioid | A | pEC50 | 5.36 | 5.38 | 5.4 | ChEMBL |
δ | OPRD | Mouse | Opioid | A | pIC50 | 5.81 | 5.91 | 6.02 | ChEMBL |
κ | OPRK | Mouse | Opioid | A | pEC50 | 5.4 | 5.4 | 5.4 | ChEMBL |