denopamine


SMILES COc1cc(CCNC[C@@H](c2ccc(cc2)O)O)ccc1OC
InChIKey VHSBBVZJABQOSG-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 317.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 8.24 8.24 8.24 Drug Central
β1 ADRB1 Human Adrenoceptors A pKi 5.8 5.95 6.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.05 5.1 5.15 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 7.7 7.7 7.7 Guide to Pharmacology
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL