CHEMBL2037530


SMILES O=C(CCCCN1CCN(c2ccccc2)CC1)c1nc2ccccc2s1
InChIKey LDOWCUPEXDHKEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.44 8.44 8.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.69 6.69 6.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database