CHEMBL2220895


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(Cl)c2O1
InChIKey CQFKZCAKNRCPDY-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 379.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Rat Adrenoceptors A pKd 8.05 8.05 8.05 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 9.04 9.3 9.56 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.05 9.05 9.05 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.66 8.66 8.66 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database