CHEMBL2220925


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(F)c2O1
InChIKey UUHRDARWBGSDJU-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 363.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rat Adrenoceptors A pKd 7.54 8.23 8.92 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.19 9.19 9.19 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.62 8.62 8.62 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.31 9.31 9.31 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.56 8.56 8.56 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.85 8.85 8.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database