ArrestinDb

CHEMBL222677

Agent/drug
Bioactivity

CHEMBL222677

SMILES	Cc1cc(Cl)ccc1-c1cccc([C@H](O)CC[C@H]2CCC(=O)N2CCc2ccc(C(=O)O)cc2)c1
InChIKey	DQBNEYSJJSAOQB-AHKZPQOWSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	9
Molecular weight (Da)	491.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pKi	4.75	4.75	4.75	ChEMBL
EP₂	PE2R2	Human	Prostanoid	A	pKi	5.29	5.29	5.29	ChEMBL
EP₃	PE2R3	Human	Prostanoid	A	pKi	4.27	4.27	4.27	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pKi	9.03	9.03	9.03	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₄	PE2R4	Human	Prostanoid	A	pEC50	10.40	10.40	10.40	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL222677

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.