CHEMBL228280


SMILES O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1cc(Cl)ccc1F
InChIKey LVDRNYWTLKUNNT-OYRHEFFESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 506.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.74 8.74 8.74 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.97 6.97 6.97 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database