glucagon
SMILES | None |
InChIKey | MASNOZXLGMXCHN-ZLPAWPGGSA-N |
Sequence | HSQGTFTSDYSKYLDSRRAQDFVQWLMNT |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Endogenous |
Approved drug | Yes |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GLP-1 | GLP1R | Human | Glucagon | B1 | pKi | 6.9 | 6.95 | 7.0 | Guide to Pharmacology |
GLP-1 | GLP1R | Human | Glucagon | B1 | pKi | 8.15 | 8.15 | 8.15 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
glucagon | GLR | Human | Glucagon | B1 | pEC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
glucagon | GLR | Mouse | Glucagon | B1 | pEC50 | 9.47 | 9.47 | 9.47 | ChEMBL |
GLP-1 | GLP1R | Human | Glucagon | B1 | pEC50 | 8.42 | 9.36 | 10.36 | ChEMBL |
glucagon | GLR | Human | Glucagon | B1 | pEC50 | 8.05 | 8.05 | 8.05 | Drug Central |
glucagon | GLR | Rat | Glucagon | B1 | pIC50 | 8.05 | 8.05 | 8.05 | Drug Central |
GLP-1 | F8V479 | Crab-eating macaque | Glucagon | B1 | pEC50 | 7.98 | 7.98 | 7.98 | Drug Central |
glucagon | GLR | Human | Glucagon | B1 | pEC50 | 10.1 | 10.16 | 10.22 | ChEMBL |
GLP-1 | GLP1R | Mouse | Glucagon | B1 | pEC50 | 7.98 | 7.98 | 7.98 | Drug Central |
GLP-1 | GLP1R | Mouse | Glucagon | B1 | pEC50 | 10.36 | 10.36 | 10.36 | ChEMBL |