GR 128107


SMILES COc1ccc2c(c1)c(c[nH]2)C1CCCN(C1)C(=O)C
InChIKey RBINAFTXZHPTNU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 272.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 6.9 6.9 6.9 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 8.6 8.85 9.1 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.1 9.1 9.1 ChEMBL
MT1 MTR1A Human Melatonin A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database