CHEMBL211590


SMILES COc1ccccc1N1CCN(Cc2cn3cc(C)cc(I)c3n2)CC1
InChIKey KESPBTDDQDBERC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 462.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.23 5.23 5.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.28 9.28 9.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.33 6.33 6.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.01 7.04 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database