CHEMBL2159471


SMILES O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)C1)c1cccs1
InChIKey GXJGVXJVSZWVLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 428.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.35 7.35 7.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database