CHEMBL2159482


SMILES O=S(=O)(NC1CCN(CCOc2cccc(F)c2)C1)c1ccc(F)c(F)c1
InChIKey KGMNPYRERCCGKH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 400.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database