iodoproxyfan


SMILES Ic1ccc(cc1)COCCCc1cnc[nH]1
InChIKey DCQNAFOCXVCDLB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 342.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 10.0 10.0 10.0 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 9.6 9.6 9.6 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 7.15 8.45 9.52 ChEMBL
H4 HRH4 Human Histamine A pKi 7.9 7.9 7.9 ChEMBL
H3 HRH3 Human Histamine A pKi 7.39 8.6 9.2 ChEMBL
H3 HRH3 Rat Histamine A pKi 8.3 9.02 9.7 PDSP Ki database
H3 HRH3 Human Histamine A pKi 9.2 9.2 9.2 PDSP Ki database
H4 HRH4 Human Histamine A pKi 7.9 7.9 7.9 PDSP Ki database
H3 HRH3 Guinea pig Histamine A pKd 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.9 7.9 7.9 ChEMBL
H3 HRH3 Human Histamine A pEC50 10.3 10.3 10.3 ChEMBL