(S)-α-methylhistamine
| SMILES | C[C@@H](Cc1cnc[nH]1)N |
| InChIKey | XNQIOISZPFVUFG-YFKPBYRVSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 2 |
| Molecular weight (Da) | 125.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H3 | HRH3 | Human | Histamine | A | pKi | 7.6 | 7.6 | 7.6 | Guide to Pharmacology |
| H4 | HRH4 | Human | Histamine | A | pKi | 5.5 | 5.5 | 5.5 | Guide to Pharmacology |
| H3 | HRH3 | Rat | Histamine | A | pKi | 6.6 | 6.6 | 6.6 | Guide to Pharmacology |
| H4 | HRH4 | Human | Histamine | A | pKi | 5.4 | 5.4 | 5.4 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pKi | 5.79 | 6.46 | 7.2 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H4 | HRH4 | Human | Histamine | A | pEC50 | 4.9 | 4.9 | 4.9 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pEC50 | 8.0 | 8.0 | 8.0 | ChEMBL |