CHEMBL2179217


SMILES COc1ccc(S(=O)(=O)n2cc(C)c3cc(Cl)ccc32)cc1NC1CCN(C)CC1
InChIKey ZPUAIXYROPYWKA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 447.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.02 6.02 6.02 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
H1 HRH1 Human Histamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.52 6.52 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database