CHEMBL219837


SMILES C[C@@H]1NCCN2C(=O)c3c(cccc3C(F)(F)F)[C@H]12
InChIKey NVKCCPZQJAJISN-CPCISQLKSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.66 7.66 7.66 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.55 7.55 7.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.11 7.11 7.11 ChEMBL