CHEMBL2397391


SMILES C#CC1=CC[C@@H](N(CCC)CCCCNC(=O)c2cc3ccccn3n2)CC1
InChIKey KVEHVMQJUPMJNA-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.35 4.35 4.35 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.55 7.38 8.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database