CHEMBL221513


SMILES N#Cc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey GKCVNAHJIZRKPK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 430.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.78 7.78 7.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 6.58 6.58 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database