CHEMBL222514


SMILES O=C1c2c(cccc2C(F)(F)F)[C@@H]2CNCCN12
InChIKey MYJCTHLPBPJBRB-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 256.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.75 6.75 6.75 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.15 8.15 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.75 6.75 6.75 ChEMBL