CHEMBL222566


SMILES C=Cc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21
InChIKey CADIZNXZPSVKJP-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 282.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 5.79 5.79 5.79 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.37 7.37 7.37 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.79 5.79 5.79 ChEMBL