CHEMBL222755


SMILES Cc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey JINXBCRENWAIPY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 419.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKd 7.8 7.8 7.8 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 5.74 5.74 5.74 ChEMBL