CHEMBL223440


SMILES CCc1cc(Cl)c2c(c1)[C@@H]1CNCCN1C2=O
InChIKey YMMIJLPGZMHLGI-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 250.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.31 7.31 7.31 ChEMBL