CHEMBL225512


SMILES O=C(CCCCCN1CCN(c2ccccc2O)CC1)NC1CCCc2ccccc21
InChIKey JYEKEEYIUIJIPG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 421.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.94 7.94 7.94 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKd 7.2 7.2 7.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.01 6.01 6.01 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.01 6.01 6.01 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database