GLAUCINE


SMILES COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3
InChIKey RUZIUYOSRDWYQF-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.55 5.55 5.55 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database