CHEMBL228738


SMILES O=C(Nc1c(F)cccc1F)C(c1ccccc1)N1CCC(O)(c2ccccc2)CC1
InChIKey ZAXWEHCCAIIFBR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 5.09 5.09 5.09 ChEMBL
δ OPRD Human Opioid A pKi 4.65 4.65 4.65 ChEMBL
κ OPRK Human Opioid A pKi 5.36 5.36 5.36 ChEMBL
μ OPRM Human Opioid A pKi 5.43 5.43 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database