CHEMBL228911


SMILES OC1(c2ccccc2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIKey VYRHTEGFBOSTMB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 411.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.7 8.7 8.7 ChEMBL
δ OPRD Human Opioid A pKi 5.78 5.78 5.78 ChEMBL
κ OPRK Human Opioid A pKi 6.2 6.2 6.2 ChEMBL
μ OPRM Human Opioid A pKi 6.59 6.59 6.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.65 6.65 6.65 ChEMBL