CHEMBL228964


SMILES COc1ccccc1C(c1ccccc1OC)N1CCC(O)(c2ccccc2)CC1
InChIKey MEIKCNSXEAPYGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.52 8.52 8.52 ChEMBL
δ OPRD Human Opioid A pKi 4.74 4.74 4.74 ChEMBL
κ OPRK Human Opioid A pKi 6.51 6.51 6.51 ChEMBL
μ OPRM Human Opioid A pKi 6.07 6.07 6.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.93 6.93 6.93 ChEMBL