CHEMBL243955


SMILES CN(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey AYPZPRUFAPTKJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 448.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.49 7.49 7.49 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Guinea pig 5-Hydroxytryptamine A pEC50 5.93 5.93 5.93 ChEMBL