CHEMBL2312641


SMILES O=S(=O)(NCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cnc2ccc(Cl)cc2c1
InChIKey IJOWGZZHIHYYGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 512.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.94 6.94 6.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database