CHEMBL2312934


SMILES O=S(=O)(NCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc2cccnc2c1
InChIKey QLYYCUQQWPWCAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 478.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.55 5.55 5.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 5.13 5.13 5.13 ChEMBL