CHEMBL234649


SMILES CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)Cc3ccccc3)CC2)CC1
InChIKey OCDNDDLEORDHLQ-PSWAGMNNSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.09 7.09 7.09 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.44 8.44 8.44 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.92 8.92 8.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database