CHEMBL25467


SMILES C=Cc1sc2ccc(Cl)c3c2c1CN(C)CC3
InChIKey WKXSXFYQPCWZOS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 263.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.64 7.66 7.7 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.5 8.7 8.8 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 8.47 8.47 8.47 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.68 7.68 7.68 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.44 7.49 7.6 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.62 7.62 7.62 ChEMBL
α1B A0A4X1U0M4 Pig Adrenoceptors A pKi 7.5 7.55 7.6 PDSP Ki database
α1A Q9TSW7 Pig Adrenoceptors A pKi 6.6 7.03 7.3 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database