CHEMBL2377443


SMILES COc1ccc2[nH]cc(C3CCN(CCCN4C(=O)CC(c5c[nH]c6ccccc56)C4=O)CC3)c2c1
InChIKey ZYUVIRYBRCERLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.49 7.49 7.49 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database