CHEMBL2397900


SMILES O=C1c2ccc(C(F)(F)F)cc2C[C@@H]2CNCCN12
InChIKey UNIHDWQKCZLGDT-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.23 6.23 6.23 ChEMBL