CHEMBL239820


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1F)c1ccccc1F)CC2
InChIKey GPNRKVNAMNPYNQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 433.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.2 8.2 8.2 ChEMBL
δ OPRD Human Opioid A pKi 4.79 4.79 4.79 ChEMBL
κ OPRK Human Opioid A pKi 6.07 6.07 6.07 ChEMBL
μ OPRM Human Opioid A pKi 6.25 6.25 6.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database