CHEMBL239821


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1cccc(F)c1)c1cccc(F)c1)CC2
InChIKey YZNPTLIZBFIOBW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 433.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.6 6.6 6.6 ChEMBL
δ OPRD Human Opioid A pKi 4.99 4.99 4.99 ChEMBL
κ OPRK Human Opioid A pKi 5.84 5.84 5.84 ChEMBL
μ OPRM Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database