ArrestinDb

CHEMBL272276

Agent/drug
Bioactivity

CHEMBL272276

SMILES	O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2ccccc2)cc1
InChIKey	IIIZQYRMSFTVQP-RWDVLYHFSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	8
Molecular weight (Da)	379.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Human	Prostanoid	A	pKi	5.59	5.59	5.59	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pKi	10.30	10.30	10.30	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Human	Prostanoid	A	pEC50	6.36	6.36	6.36	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pEC50	10.52	10.52	10.52	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL272276

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.