CHEMBL240022


SMILES COc1cc2c(cc1OC)CN(/C=N/c1ccc3c(c1)C(OC(C)=O)CCC3)CC2
InChIKey LHDVHKCXIMBGFK-MFKUBSTISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.7 6.7 6.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.96 4.96 4.96 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database