CHEMBL2414358


SMILES Clc1ccc(-n2cc(CCCCCN3CCN(c4ccccc4)CC3)cn2)cc1
InChIKey MKRMGDJUMMLQKR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 408.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Rat Adrenoceptors A pKi 6.42 6.42 6.42 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.31 6.31 6.31 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.93 5.93 5.93 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database