CHEMBL280586


SMILES CCCN(CCCNS(=O)(=O)c1ccc(C)cc1)C1COc2cccc(OC)c2C1
InChIKey AQJAKCNEOWYUTG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 432.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 5.22 5.22 5.22 ChEMBL
α2A ADA2A Bovine Adrenoceptors A pIC50 6.3 6.3 6.3 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 5.52 5.52 5.52 ChEMBL
D1 DRD1 Bovine Dopamine A pIC50 4.7 4.7 4.7 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 7.52 7.52 7.52 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.52 8.52 8.52 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 5.7 5.7 5.7 ChEMBL