CHEMBL243744


SMILES CC(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey CPWLTNLRAGBWKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 447.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Guinea pig 5-Hydroxytryptamine A pEC50 6.05 6.05 6.05 ChEMBL