CHEMBL243953


SMILES CC(C)(C)c1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc32)CC1
InChIKey BLCHSWWAUDRFLL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 461.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database