ArrestinDb

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Ligand source activities (1 row/activity)

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	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

[D-Phe⁶,β-Ala¹¹,Phe¹³,Nle¹⁴]bombesin-(6-14)	1478	None	0	Human	Binding	pKi	=	-	8.75	-1	5	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10454496
[D-Phe⁶,β-Ala¹¹,Phe¹³,Nle¹⁴]bombesin-(6-14)	1478	None	0	Human	Binding	pKi	=	-	8.75	-1	5	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/21729729
[Leu⁸]-phyllolitorin	2307	None	0	Rat	Binding	pKi	>	-	5.00	-23	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9325344
[Leu⁸]-phyllolitorin	2307	None	0	Rat	Binding	pKi	>	-	5.00	-23	4	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10353842
[Phe¹³]bombesin	3102	None	0	Rat	Binding	pKi	=	-	7.34	-58	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10454496
[Phe¹³]bombesin	3102	None	0	Rat	Binding	pKi	=	-	7.34	-58	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9325344
[Phe¹³]bombesin	3102	None	0	Rat	Binding	pKi	=	-	7.34	-58	3	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10353842
bag-1	569	None	23	Human	Binding	IC50	=	7000.00	5.16	-	5	Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from human NMB-R expressed in NFAT-CHO cells after 2 hrs by scintillation counting	ChEMBL	333.2	7	1	2	5.24	CCC(C)(C)Cc1cnc(CCc2ccc(-c3ccccn3)cc2)[nH]1	https://dx.doi.org/10.1016/j.bmcl.2010.02.076
bombesin	704	None	34	Human	Binding	pKi	=	-	7.48	-7	6	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10454496
bombesin	704	None	34	Human	Binding	pKi	=	-	7.48	-7	6	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/7838118
bombesin	704	None	34	Human	Binding	Ki	=	2.00	8.70	-7	6	Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cells	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1016/0960-894X(96)00481-7
bombesin	704	None	34	Rat	Binding	pKi	=	-	7.57	-24	6	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/10454496
bombesin	704	None	34	Rat	Binding	pKi	=	-	7.57	-24	6	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/7838118
CHEMBL100065	4172	None	0	Human	Binding	IC50	=	790.00	6.10	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	633.4	8	4	3	8.75	Cc1ccc2[nH]c3c(c2c1)C(C)C(NC(=O)Nc1c(C(C)C)cccc1C(C)C)(C(=O)NCC1(c2ccccn2)CCCCC1)CC3	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL100065	4172	None	0	Human	Binding	IC50	=	700.00	6.16	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	633.4	8	4	3	8.75	Cc1ccc2[nH]c3c(c2c1)C(C)C(NC(=O)Nc1c(C(C)C)cccc1C(C)C)(C(=O)NCC1(c2ccccn2)CCCCC1)CC3	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL101026	4343	None	0	Human	Binding	IC50	=	660.00	6.18	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	619.4	8	4	3	8.19	Cc1cccc2[nH]c3c(c12)CC(NC(=O)Nc1c(C(C)C)cccc1C(C)C)(C(=O)NCC1(c2ccccn2)CCCCC1)CC3	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL102647	4590	None	0	Human	Binding	IC50	=	2140.00	5.67	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	683.3	8	4	3	8.64	CC(C)c1cccc(C(C)C)c1NC(=O)NC1(C(=O)NCC2(c3ccccn3)CCCCC2)CCc2[nH]c3cc(Br)ccc3c2C1	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL103430	4697	None	0	Human	Binding	IC50	=	3660.00	5.44	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	673.4	8	4	3	8.90	CC(C)c1cccc(C(C)C)c1NC(=O)NC1(C(=O)NCC2(c3ccccn3)CCCCC2)CCc2[nH]c3cccc(C(F)(F)F)c3c2C1	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL103439	4699	None	0	Human	Binding	IC50	=	620.00	6.21	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	580.3	7	4	5	5.85	Cc1cc([N+](=O)[O-])ccc1NC(=O)NC1(C(=O)NCC2(c3ccccn3)CCCCC2)CCc2[nH]c3ccccc3c2C1	https://dx.doi.org/10.1016/j.bmcl.2004.04.045
CHEMBL103440	4700	None	0	Human	Binding	IC50	=	800.00	6.10	-	1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	ChEMBL	566.3	7	4	5	5.54	O=C(Nc1ccc([N+](=O)[O-])cc1)NC1(C(=O)NCC2(c3ccccn3)CCCCC2)CCc2[nH]c3ccccc3c2C1	https://dx.doi.org/10.1016/j.bmcl.2004.04.045

Showing 1 to 20 of 183 entries

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

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Ligand source activities (1 row/activity)