ArrestinDb

	Ligands				Receptor	Activity									Chemical information
	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

Ligands				Receptor	Activity									Chemical information
Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI

(D-Thr⁶, D-Trp^8,9)galanin(1-15)ol	1494	None	0	Rat	Binding	pKi	>	-	6.00	1	2	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9405385
[Ala⁶, D-Trp⁸]galanin-(1-15)-ol	337	None	0	Rat	Binding	pKi	=	-	7.75	-	1	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9405385
[D-Trp²]galanin-(1-29)	1499	None	0	Human	Binding	Kd	=	69.00	7.16	-173	4	Binding affinity to human GalR3	ChEMBL	-	-	-	-	-	-	https://dx.doi.org/10.1021/jm801088x
C7	777	None	0	Human	Binding	pKi	=	-	8.08	-34	8	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9722565
C7	777	None	0	Human	Binding	pKi	=	-	8.08	-34	8	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9880084
C7	777	None	0	Rat	Binding	pKi	=	-	8.73	-7	8	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9722565
C7	777	None	0	Rat	Binding	pKi	=	-	8.73	-7	8	Unclassified	Guide to Pharmacology	-	-	-	-	-	-	https://pubmed.ncbi.nlm.nih.gov/9405385
CHEMBL209476	77952	None	0	Human	Binding	Ki	=	45.00	7.35	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	509.2	10	0	4	7.00	CCN(CC)CCCCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL209480	77955	None	11	Human	Binding	Ki	=	596.00	6.22	-	1	Displacement of [125I]galanin from human GAL3	ChEMBL	290.1	1	1	2	3.78	O=C1Nc2ccccc2/C1=N\c1cccc(C(F)(F)F)c1	https://dx.doi.org/10.1021/jm060001n
CHEMBL209481	77956	None	0	Human	Binding	Ki	=	87.00	7.06	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	481.2	8	0	4	6.22	CCN(CC)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL209498	77958	None	0	Human	Binding	Ki	=	8.00	8.10	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	493.2	6	0	4	6.37	O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCCC2)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL209642	77982	None	0	Human	Binding	Ki	=	27.00	7.57	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	511.2	9	1	5	5.59	CCN(CC)C[C@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL209730	78030	None	0	Human	Binding	Ki	=	89.00	7.05	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	453.2	6	0	4	5.45	CN(C)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL209737	78032	None	32	Human	Binding	Ki	=	850.00	6.07	-	1	Displacement of [125I]galanin from human GAL3	ChEMBL	256.0	1	1	2	3.41	O=C1Nc2ccccc2/C1=N\c1ccc(Cl)cc1	https://dx.doi.org/10.1021/jm060001n
CHEMBL211031	78405	None	0	Human	Binding	Ki	=	49.00	7.31	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	493.2	7	0	4	6.37	O=C1/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL211169	78489	None	0	Human	Binding	Ki	=	52.00	7.28	-	1	Displacement of [125I]galanin from human GAL3	ChEMBL	360.1	4	0	2	5.36	CCC(CC)N1C(=O)/C(=N/c2ccc(C(F)(F)F)cc2)c2ccccc21	https://dx.doi.org/10.1021/jm060001n
CHEMBL211398	79555	None	0	Human	Binding	Ki	=	26.00	7.58	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	453.2	6	0	4	5.45	CN(C)CCOc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL211467	79639	None	0	Human	Binding	Ki	=	78.00	7.11	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	481.2	8	0	4	6.22	CCN(CC)CCOc1ccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)cc1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL211522	79698	None	0	Human	Binding	Ki	=	290.00	6.54	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	511.2	9	1	5	5.59	CCN(CC)C[C@@H](O)COc1cccc(N2C(=O)/C(=N/c3cccc(C(F)(F)F)c3)c3ccccc32)c1	https://dx.doi.org/10.1016/j.bmcl.2006.05.025
CHEMBL212224	79886	None	0	Human	Binding	Ki	=	1000.00	6.00	-	1	Displacement of [125I]galanin from human galanin Gal3 receptor	ChEMBL	481.2	8	0	4	6.22	CCN(CC)CCOc1ccccc1N1C(=O)/C(=N/c2cccc(C(F)(F)F)c2)c2ccccc21	https://dx.doi.org/10.1016/j.bmcl.2006.05.025

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Ligand source activities (1 row/activity)