ArrestinDb
Arrestins can 'arrest' signaling by blocking GPCR-mediated G protein coupling and inducing receptor internalization.
They are also scaffold proteins rectruiting and assembling other signaling proteins and can be involved in biased
signaling1
Data
- Sequences
- 4 Human arrestins
- 90 Species orthologs
- Couplings
- 300 Arrestin couplings
- Structures
- 60 Arrestins
- 458 Generic residues
- 12 Arrestin complexes
- Structure interactions
- 334,216 Interface interactions
- Mutations
- 409 Interface mutations